Condition of the heat stroke model and body weight (BW) during the experiment. (A) Transition of ambient temperature (AT), relative humidity (RH), and wet bulb globe temperature (WBGT) before and during heat exposure. AT and RH inside the chamber were 38.1 °C and >99.9%, and WBGT was calculated at 42 °C. AT and WBGT temporarily decreased when the animals were placed in the chamber, and after 60 min, AT and WBGT gradually increased, reaching 39.9 and 43.9 °C, respectively. (B) Compared with the BWs before hydration, which was 100%, after 1 h of heat exposure, they decreased and mostly returned to baseline levels after 1 day. No significant difference was observed in BW during the experimental periods.