Table 4.
miRNA expression in EVs of patients with low Vit.D levels who underwent Vit.D supplementation. Relative expression levels of miRNAs obtained by qRT-PCR on representative patients classified according to SARS-CoV-2 IgG status are shown prior to and following Vit.D treatment. In red: downregulation of expression with respect to starting level of expression. P1, P2, and P3 are three patients who had low Vit.D levels and underwent Vit.D supplementation.
| miRNA | Low Vit.D | Vit.D Supplemented | ||||
|---|---|---|---|---|---|---|
| P1 (SARS-CoV-2+) | P2 (SARS-CoV-2+) | P3 (SARS-CoV-2−) | P1 (SARS-CoV-2+) | P2 (SARS-CoV-2+) | P3 (SARS-CoV-2−) | |
| Let-7a-5p | 1.65148345 | 0.967622724 | 0.511047209 | 2.627095884 | 2.846824659 | 0.837721773 |
| Let-7f-5p | 1.600454936 | 0.723943443 | 0.303769668 | 3.508573233 | 3.54355914 | 0.876204496 |
| miR150-5p | 1.645731544 | 1.614814116 | 1.11826679 | 2.655071171 | 3.350935823 | 1.013703793 |
| miR30d-5p | 1.405683671 | 1.186686379 | 0.5156357 | 3.506820284 | 5.054646657 | 1.130965628 |