Table 1.
Patients’ main clinical and demographic characteristics.
| <29 Weeks | ≥29 Weeks | p-Value | |
|---|---|---|---|
| # of patients (%) | 11 (46) | 13 (54) | 0.68 |
| Gestational age (median; IQR) | 26; 3 | 31; 4 | <0.001 |
| Birth weight (mean ± SD) | 784 ± 250 g | 1594 ± 473 g | <0.001 |
| APGAR 1′ (median; IQR) | 5; 4 | 6; 3 | 0.14 |
| APGAR 5′ (median; IQR) | 8; 2.5 | 8; 0 | 0.25 |
| UA pH at birth (mean ± SD) | 7.21 ± 0.07 | 7.19 ± 0.12 | 0.17 |
| UA BE at birth (mean ± SD) | −6.2 ± 1.5 | −8.6 ± 4.3 | 0.08 |
| Low-grade GMH-IVH (US/MRI) | 1/2 | 0 | 0.25 * |
| CBH | 0/1 (punctate lesions) | 0/1 (punctate lesions) | 1 * |
| Adverse events during/after ES | 0 | 0 | 1 |
#, number; SD, standard deviation; IQR, interquartile range; UA, umbilical artery; BE, base excess; GMH-IVH, germinal matrix/intraventricular hemorrhage; CBH, cerebellar hemorrhage; US, detected by cranial ultrasound; MRI, detected by brain MRI; ES, exogenous surfactant. * p-value calculated considering the gold standard methodology of brain MRI.