Table 2.

Univariate and stepwise forward multivariate regression analysis for associations between clinical characteristics and serum Klotho concentrations (log-normalized values)

	Univariate				Multivariable*
	Coefficients	Beta	t	p	Coefficients	Beta	t	p
Female gender	0.027	0.091	4.53	< 0.001	0.021	0.069	3.45	< 0.001
Age, /10 years	-0.012	-0.086	-4.27	< 0.001	-0.011	-0.079	-3.99	< 0.001
BMI category	-0.024	-0.066	-3.30	0.001	-0.025	-0.069	-3.46	< 0.001
Tobacco use	-0.015	-0.108	-5.38	< 0.001	-0.014	-0.100	-4.95	< 0.001
WC, /10 cm	-0.003	-0.036	-1.80	0.072	-
SBP, /10mmHg	-0.003	-0.033	-1.62	0.104	-
MAP, /10mmHg	-0.002	-0.015	-0.76	0.446	-
PP, /10mmHg	-0.003	-0.034	-1.67	0.095	-

BMI, body mass index, and BMI category include four levels (< 18.5 kg/m², 18.5–25 kg/m², 25–29.9 kg/m², and > 30 kg/m²); WC, waist circumference; SBP, systolic blood pressure; MAP, mean artery pressure; PP, pulse pressure; tobacco use includes four levels (none, quit, some days, and every day). ^*Stepwise forward regression model after adjusting for ethnicity