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. 2024 Sep 27;24:198. doi: 10.1186/s12902-024-01737-8

Table 3.

Spearman’s rank correlation between serum Klotho and laboratory parameters

Total Men Women
Rho t p Rho t p Rho t p
Hemoglobin (g/dl) 0.036 1.808 0.071 0.153 5.319 < 0.001 0.033 1.182 0.237
Albumin (g/dl) -0.017 -0.845 0.398 0.058 1.992 0.047 -0.045 -1.603 0.109
Creatinine (mg/dl) -0.151 -7.609 < 0.001 -0.097 -3.367 < 0.001 -0.130 -4.702 < 0.001
Uric acid (mg/dl) -0.180 -9.091 < 0.001 -0.142 -4.954 < 0.001 -0.185 -6.730 < 0.001
Urea nitrogen (mg/dl) -0.075 -3.760 < 0.001 -0.039 -1.353 0.176 -0.085 -3.039 0.002
FPG (mg/dl) 0.043 1.497 0.135 0.078 1.906 0.057 0.023 0.568 0.570
A1c (%) 0.024 1.178 0.239 0.035 1.218 0.224 0.010 0.362 0.717
Cholesterol (mg/dl) -0.0004 -0.021 0.983 -0.020 -0.685 0.494 -0.007 -0.257 0.797
Triglycerides (mg/dl) -0.059 -2.941 0.003 0.003 0.107 0.915 -0.116 -4.189 < 0.001
LDL (mg/dl) 0.007 0.257 0.797 0.023 0.556 0.579 -0.020 -0.483 0.629
HDL (mg/dl) 0.028 1.377 0.169 -0.070 -2.428 0.015 0.077 2.748 0.006
WBC count (1000 cells/ul) -0.061 -3.022 0.003 -0.031 -1.064 0.288 -0.093 -3.337 0.001
hs-CRP (mg/l) -0.046 -2.277 0.023 -0.077 -2.658 0.008 -0.037 -1.312 0.190
SHBG (nmol/l) 0.074 3.698 < 0.001 0.083 2.861 0.004 0.030 1.065 0.287
Estradiol (pg/ml) 0.046 2.287 0.022 0.083 2.862 0.004 0.080 2.890 0.004
Testosterone (ng/dl) -0.036 -1.776 0.076 0.093 3.215 0.001 0.040 1.423 0.155

LDL, fasting low-density lipoprotein cholesterol level; HDL, fasting high-density lipoprotein cholesterol level; FPG, fasting plasma glucose; WBC, white blood cell; hs-CRP, high-sensitivity C-reactive protein; SHBG, sex hormone binding globulin