Table 4.
Gender-specific stepwise forward multivariate regression analysis for independent associations with Klotho*
| Coefficients | Beta | t | p | |
|---|---|---|---|---|
| Men | ||||
| Uric acid (mg/dl) * | -0.126 | -0.085 | -2.725 | 0.007 |
| Estradiol (pg/ml) * | 0.069 | 0.081 | 2.751 | 0.006 |
| HDL (mg/dl) * | -0.182 | -0.171 | -5.500 | < 0.001 |
| SHBG (nmol/l) * | 0.114 | 0.167 | 4.872 | < 0.001 |
| Tobacco use | -0.012 | -0.090 | -3.062 | 0.002 |
| Age/10 | -0.009 | -0.070 | -2.224 | 0.026 |
| Creatinine (mg/dl) * | -0.084 | -0.064 | -2.071 | 0.039 |
| CRP (mg/l) * | -0.017 | -0.062 | -2.068 | 0.039 |
| Women | ||||
| Uric acid (mg/dl) * | -0.137 | -0.102 | -3.361 | 0.001 |
| Tobacco use | -0.013 | -0.086 | -3.084 | 0.002 |
| Creatinine (mg/dl) * | -0.117 | -0.091 | -3.005 | 0.003 |
| Triglycerides (mg/dl) * | -0.039 | -0.063 | -2.152 | 0.032 |
| Age/10 years | -0.010 | -0.067 | -2.330 | 0.020 |
| WBC* | -0.072 | -0.061 | -2.038 | 0.042 |
HDL, fasting high-density lipoprotein cholesterol level; FPG, fasting plasma glucose; WBC, white blood cell. Tobacco use includes four levels (none, quit, some days, and every day). * Log-normalized values