Table 3.
Correlation between expression levels and severity of disease phenotype.
snb-1p:: Aβ1-42 | rgef-1p:: Aβ1-42 | unc-119p:: Aβ1-42 | |
---|---|---|---|
Expression level | High | Medium | Low |
Lifespan | 3 | 2 | 1 |
Brood size | 3 | 2 | 1 |
Egg retention | 3 | 2 | 1 |
Chemotaxis (diacetyl) | 3 | 2 | 1 |
Motility on solid media | 3 | 3 | 1 |
Motility in liquid media | 3 | 2 | 1 |
Basal slowing response | 3 | 3 | NA |
The difference in severity across the various phenotypes is combined with Aβ expression levels in this table to develop an overall phenotype score. Phenotypic severity, combined with expression levels, is color-coded as follows: red for severe, yellow for moderate, and blue for mild. NA: Not Applicable.