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Maps of AAV vector constructs. Linear maps of the AAV gene cassettes used for this study. AAV2-ITR = inverted terminal repeat sequence from AAV2, CMVe = CMV immediate early enhancer, ACTpro = chicken β-actin promoter, Hybrid IVS = hybrid intron with upstream portion from chicken β-actin and downstream portion from rabbit β-globin, hSERPINA1= human SERPINA1 coding sequence, rhSERPINA1-myc = rhesus SERPINA1 coding sequence with c-myc epitope tag fusion, pA = SV40 polyadenylation signal.
