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. 2024 Sep 18;13(18):2943. doi: 10.3390/foods13182943

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of Basella alba extracts on mRNA expression of (a) MITF, (b) TYR, (c) TRP-1, (d) DCT, and (e) MC1R in IBMX-induced human melanoma cells. Data are presented as mean ± SD (n = 3). Statistical significance in the comparison among all extracts is indicated by different letters (a, b, and c), with significance defined as p < 0.05, as established through one-way ANOVA and subsequent LSD post hoc comparison. IBMX: 3-isobutyl-1-methylxanthine; Ar: arbutin; Water: aqueous extract of Basella alba; 50 EtOH: 50% ethanolic extract of Basella alba; 95 EtOH: 95% ethanolic extract of Basella alba.