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. 2024 Oct;30(10):2056–2069. doi: 10.3201/eid3010.240084

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Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Kaplan-Meier survival plots calculated for C57BL/6 mice exposed to aerosolized Burkholderia pseudomallei ATS2021, the causative strain in an outbreak of 4 cases, 2 of them fatal, in the United States in 2021. A) Survival after 21 days; B) survival after 60 days. N = 10 per aerosolized dose of B. pseudomallei. The day 21 survival rates from highest to lowest calculated inhaled dose of B. pseudomallei ATS2021 (4,490 CFU, 1,150 CFU, 107 CFU, 13 CFU, 1 CFU) as depicted in panel A are 0/10, 0/10, 4/10, 8/10, and 10/10. The day 60 survival rates from highest to lowest calculated inhaled dose of B. pseudomallei ATS2021 as depicted in panel B are 0/10, 0/10, 0/10, 3/10, and 9/10.