| ACE2 | angiotensin-converting enzyme 2 |
| ACL | ATP-dependent citrate lyase |
| ACO1 | cytoplasmic aconitase |
| ACP | accessory protein |
| AECs | airway epithelial cells |
| a-KG | a-ketoglutarate |
| AKI | acute kidney injury |
| Akt | protein kinase B |
| AMs | alveolar macrophages |
| AMPK | AMP-activated protein kinase |
| AP-1 | activator protein 1 |
| Asp | aspartate |
| BEC | bronchial epithelial cell |
| BMDM | bone marrow-derived macrophages |
| BOT | benfooxythiamine |
| C1 | one-carbon metabolism |
| CARKL | carbohydrate kinase-like protein |
| Cit | citrate |
| CKI | chronic kidney injury |
| CLR | C-type lectin receptor |
| CMs | cardiomyocytes |
| CNS | central nervous system |
| CoA | coenzyme A |
| CS | citrate synthase |
| d-ALA | d-aminolevulinic acid |
| DC | dentritic cell |
| DEGs | differentially expressed genes |
| 2-DG | 2-deoxyglucose |
| DON | diazo-oxo-norleucine |
| dpi | days post infection |
| EnCs | endothelial cells |
| EpCs | epithelial cells |
| EGFR | epidermal growth factor receptor |
| ERBB2 | epidermal growth factor receptor 2 |
| ETC | electron transport chain |
| FPP | fructose-1,6-diphosphate |
| FAO | fatty acid oxidation |
| FAS | fatty acid synthesis |
| FBs | fibroblasts |
| FCS | bovine calf serum |
| Fum | fumarate |
| FUM | fumarase |
| G6P | glucose-6-phosphate |
| GABA | g-aminobutyric acid |
| GAP | glyceraldehyde-3-phosphate |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
| GCs | goblet cells |
| GI | gastrointestinal |
| Gln | glutamine |
| Glu | glutamate |
| GLUT | glucose transporter |
| GLS | glutamate synthase |
| GN | gluconeogenesis |
| GP73 | Golgi protein 73 |
| GRP78 | glucose-regulated protein 78 |
| HAE | human airway epithelial |
| HCV | hepatitis C virus |
| HIF-1 | hypoxia-inducible transcription factor 1 |
| HK-1 | hexokinase 1 |
| HK-2 | hexokinase 2 |
| HMC3 | human microglial clone 3 |
| hPSCs | human pluripotent stem cells |
| HUVECs | human umbilical vein endothelial cells |
| Ica | itaconate |
| Icit | isocitrate |
| IDH1 | isocitrate dehydrogenase 1 |
| IE | intestinal epithelium |
| IFN | interferon |
| IL | interleukin |
| IMs | interstitial macrophages |
| iNOS | inducible NO synthase |
| ISCs | intestinal stem cells |
| ISGs | interferon stimulated genes |
| LDH | lactate dehydrogenase |
| LDH-A | lactate dehydrogenase A |
| LDH-B | lactate dehydrogenase B |
| LFA-1 | lymphocyte function-associated antigen |
| LKB1 | liver kinase B1 |
| LPS | lipopolysaccharide |
| LRT | lower respiratory tract |
| Mal | malate |
| MDH1 | malate dehydrogenase 1 |
| MDMs | monocyte derived macrophages |
| MERS | Middle East Respiratory Syndrome |
| moDCs | DCs dervied from blood monocytes |
| MOI | multiplicity of infection |
| MP | macrophage |
| MPC | mitochondrial pyruvate carrier complex |
| MR | mannose receptor |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase 2 |
| mTOR | mammalian target of rapamycin |
| mTORC1 | mammalian target of rapamycin complex 1 |
| mTORC2 | mammalian target of rapamycin complex 2 |
| Myc | myelocytomatosis oncogene |
| NE | nasal epithelium |
| NECs | nasal epithelial cells |
| NETs | neutrophil extracellular traps |
| NFAT | nuclear factor of activated T-cells |
| NF-κB | nuclear factor 'kappa-light-chain-enhancer' of activated B-cells |
| NK | natural killer |
| NRP1 | neuropilin-1 |
| NSCLC | non-small cell lung cancer |
| NSP | non-structural protein |
| NTPs | nucleoside triphosphates |
| OAA | oxaloacetate |
| OGDC | oxoglutarate dehydrogenase complex |
| OXPHOS | oxidative phosphorylation |
| PASC | post-acute sequelae of SARS-CoV-2 infection |
| PBMCs | peripheral blood mononuclear cells |
| PC | pyruvate carboxlyase |
| PCs | Paneth cells |
| PDH | pyruvate dehydrogenase |
| PDHK | pyruvate dehydrogenase kinase |
| PEP | phosphoenolpyruvate |
| PEPCK | phosphoenolpyruvate carboxykinase |
| PFK-1 | phosphofructokinase 1 |
| pi | post infection |
| PI3K | phosphoinositide-3-kinase |
| PK | pyruvate kinase |
| PKM-2 | pyruvate kinase isoenzyme 2 |
| PMA | phorbol-12-myristate-13-acetate |
| PPP | pentose phosphate pathway |
| PRPP | phosphoribosyl diphosphate |
| PRVs | positive-sense single strand RNA viruses |
| PTCs | proximal tubular cells |
| PTEN | phosphatase and tensin homolog |
| Pyr | pyruvate |
| R5P | ribose-5-phosphate |
| RB | retinoblastoma protein |
| RBD | receptor binding domain |
| RdRp | RNA-dependent RNA polymerase |
| Ribu5P | ribulose-5-phosphate |
| ROS | reactive oxygen species |
| RTC | replication/transcription complex |
| SARS-CoV | Severe Acute Respiratory Syndrome Coronavirus |
| SARS-CoV-2 | Severe Acute Respiratory Syndrome Coronavirus 2 |
| SCS | succinyl-CoA synthetase |
| SDH | succinate dehydrogenase |
| SIRT | sirtuin |
| SP | structural protein |
| ssRNA | single-stranded RNA |
| Suc | succinate |
| Suc-CoA | succinyl-CoA |
| TCA cycle | tricarboxylic acid cycle |
| TCR | T-cell receptor |
| TGF | transforming growth factor |
| TKT | tranketolase |
| TLR | Toll-like receptor |
| TMPRSS2 | transmembrane protease serine subtype 2 |
| TNF | tumor necrose factor |