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. 2024 Sep 2;14(9):1103. doi: 10.3390/life14091103

Table 2.

DAVID analysis of SCL-upregulated NRL targets. This table displays relevant Gene Ontology (GO) terms and genes that could be associated with synapse development.

GOterm Go ID Genes
actin binding 0003779 DIAPH3, PARVG, WIPF1, EPB41L1, MYO7A, CAP2
dendrite 0030425 ACHE, OPN4, NEGR1, NR1D1, IGSF9, CNNM4
actin cytoskeleton 0015629 RINL, PARVG, WIPF1, MYO7A
cell morphogenesis 0000902 GREM1, GNAT2, CAP2
ATP-dependent microtubule motor activity, minus-end-directed 0008569 KIFC1, DNAH7C
axon 0030424 ACHE, OPN4, MAP4, IGSF9, DCLK1
amino acid transmembrane transport 0003333 SLC7A8, SLC38A3
microtubule 0005874 KIFC1, MAP4, DNAH7C
calcium ion binding 0005509 HEG1, CALU, SPOCK1, AMY1, DNAH7C
extracellular region 0005576 GREM1, ACHE, ORM1, CALU, SPOCK1, AMY1

25 genes: ACHE, AMY1, CALU, CAP2, CNNM4, DCLK1, DIAPH3, DNAH7C, EPB41L1, GNAT2, GREM1, HEG1, IGSF9, KIFC1, MAP4, MYO7A, NEGR1, NEGR1, OPN4, ORM1, PARVG, RINL, SLC38A3, SLC7A8, SPOCK1, WIPF1. SynGO analyses also provided genes underlined.