Table 1.
Epidemiological, clinical, therapeutic and outcome data of 43 patients with non-zoonotic sporotrichosis followed at INI/Fiocruz, Rio de Janeiro, Brazil, between 2005 and 2020.
| Variable | Description | N (%) |
|---|---|---|
| Epidemiology | Plants and/or soil manipulation | 21 (48.8%) |
| Unknown | 12 (27.9%) | |
| Insect bites | 4 (9.4%) | |
| Previous trauma * | 2 (4.7%) | |
| Human aggression | 1 (2.3%) | |
| Human bite | 1 (2.3%) | |
| Trauma with iron gate | 1 (2.3%) | |
| Trauma with fishbone | 1 (2.3%) | |
| Clinical form | Lymphocutaneous | 28 (65%) |
| Fixed cutaneous | 10 (23.3%) | |
| Cutaneous disseminated | 2 (4.7%) | |
| Unifocal extracutaneous ** | 2 (4.7%) | |
| Disseminated | 1 (2.3%) | |
| Treatment | Itraconazole | 27 (62.9%) |
| Terbinafine | 3 (7%) | |
| Change in treatment | Itraconazole to terbinafine Itraconazole to amphotericin B Itraconazole to terbinafine to amphotericin B Itraconazole to posaconazole |
4 (9.3%) |
| 1 (2.3%) | ||
| 1 (2.3%) | ||
| 1 (2.3%) | ||
| Adjuvant treatment | Cryosurgery associated with itraconazole Cryosurgery associated with itraconazole and terbinafine Cryosurgery associated with terbinafine Cryosurgery Warm water compress |
2 (4.7%) |
| 1 (2.3%) | ||
| 1 (2.3%) | ||
| 1 (2.3%) | ||
| 1 (2.3%) | ||
| Outcome | Clinical cure | 35 (81.4%) |
| Lost to follow-up | 6 (13.9%) | |
| Still under treatment | 2 (4.7%) |
* The patients confirmed that they had had contact with animals, especially cats. ** Extracutaneous: ocular and pulmonary involvement (one case each).