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. 2024 Aug 28;14(9):915. doi: 10.3390/jpm14090915

Table 1.

OHSS classification.

Symptoms
Frequency
Always Usually Often Rarely
Mild
OHSS
Enlargement of bilateral ovaries with multiple follicular. Corpus luteal cysts, measuring up to 8 cm. Abdominal bloating and mild abdominal pain.
Moderate OHSS Ovaries up to 12 cm. Abdominal bloating due to an increase in ovarian size. Gastrointestinal symptoms (nausea, vomiting and diarrhea). Ultrasound evidence of ascites and rapid weight gain of over 2.5–3 kg.
Severe OHSS Large ovarian cysts (>12 × 12 cm), clinical ascites with or without hydrothorax. Hyperkalemia (potassium > 5 mmol/L), hyponatremia (sodium < 135 mmol/L). Oliguria (<300 mL/d or
<30 mL/h), creatinine 1.1–1.5 mg/dL, and
hypovolemic shock. Hemoconcentration with
hematocrit > 45%, white cell count > 15,000.
Liver dysfunction, increased blood viscosity, and thromboembolic.
Critical
OHSS
Severe ascites or hydrothorax, hematocrit > 55%, white cell count > 25,000/mL. Oliguria or anuria, creatinine ≥ 1.6 mg/dL,
creatinine clearance < 50 mL/min.
Thromboembolism, or acute
respiratory distress syndrome.