Table 4.

The theoretical values of lipophilicity for betulin and its indole derivatives.

Compound	iLOGP	XLOPG2	XLOGP3	WLOGP	MLOGP	SILICOS-IT	MilogP	ACD/logP	KOWWIN	ALOGPs
Betulin	4.31	7.82	8.28	7.00	6.00	6.21	7.16	9.01	8.18	5.34
EB355A	4.89	10.15	10.58	9.27	6.61	8.74	8.96	11.62	10.54	6.65
EB365	5.39	10.89	11.15	9.84	6.85	9.27	9.20	12.52	11.55	7.22
EB366	5.70	10.89	11.15	9.84	6.85	9.27	9.08	12.52	11.55	7.25
EB367	5.32	10.15	10.58	9.27	6.61	8.74	8.81	11.62	10.54	6.73