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. 2024 Sep 16;29(18):4408. doi: 10.3390/molecules29184408

Table 8.

Correlation analysis between the IC50 values for MCF-7 and the other values analyzed for the compounds EB355A, EB366 and EB367.

MCF-7 [IC50 µM] MCF-7 [IC50 µM]
RM0 0.340 KOWWIN 0.262
LogPTLC 0.342 ALOGPs 0.219
iLOGP −0.123 M [g/mol] 0.262
XLOGP2 0.262 TPSA [Å2] 0.262
XLOGP3 0.262 nROTB 0.262
WLOGP 0.262 nHBD −0.262
MLOGP 0.262 nHBA 0.262
SILCOS-IT 0.262 MR 0.262
milogP 0.710 LogPapp −0.183
ACD/logP 0.262 LogKp −0.068