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. 2024 Sep 3;12(9):1821. doi: 10.3390/microorganisms12091821

Table 6.

The number of probiotic bacteria DNA copies per 100,000 of 16S gene in 1 μL of extracted material.

Placebo Cohort, n = 13 Probiotic Cohort, n = 18 p Value
L. plantarum
Baseline
Mean + SE 197,482 + 195,685 999 + 681 1
30 days intervention
Mean + SE 240 + 257 * 10,681 + 7883 0.047
30 days follow-up
Mean + SE 5081 + 3775 * 412 + 393 0.466
L. brevis
Baseline
Mean + SE 7 + 4 737 + 709 1
30 days intervention
Mean + SE 14 + 9 * 26,708 + 26,335 0.304
30 days follow-up
Mean + SE 77,301 + 77,300 * 125 + 90 0.079
P. acidilactici
Baseline
Mean + SE 839,724 + 795,780 141,452 + 125,536 1
30 days intervention
Mean + SE 2933 + 2917 * 36,180 + 288,769 0.584
30 days follow-up
Mean + SE 807,375 + 470,904 * 21,348 + 20,908 0.823

* Differences between probiotic DNA levels in intervention and follow-up samples in the placebo cohort were not statistically different compared to the probiotic DNA levels at baseline (p = 0.46–0.88). Differences between probiotic DNA levels in intervention and follow-up samples in the probiotic cohort were not statistically different compared to the probiotic DNA levels at baseline (p = 0.06–0.99).