ACAN	aggrecan
ACTL	anterior cruciate ligament transection
ADAMTS	a disintegrin and metalloproteinase with thrombospondin motifs
AKT	a serine/threonine protein kinase
ALP	alkaline phosphatase
AP-1	activator protein 1
BAX	Bcl-2-associated X protein
BCL-2	B cell lymphoma-2
BMSC	bone marrow stromal cells
C/EBP	CCAAT/enhancer-binding protein
CASP	caspase
c-FOS	fos proto-oncogene
COL	collagen
COMP	cartilage oligomeric matrix protein
COX2	clyclooxygenase 2
CRP	C-reactive protein
DHA	docosahexaenoic acid
DMSO	dimethylsulphoxide
DNMT	DNA methyltransferase
DOT1L	disruptor of telomeric silencing 1-like
ECM	extracellular matrix
EPA	eicosapentaenoic acid
ER	endoplasmatic reticulum
ERK	extracellular signal-regulated kinase
FLS	fibroblast-like synoviocytes
FOXO	forkhead box O
GAG	glycosaminoglycan
HAT	histone acetyltransferase
HDAC	histone deacetylases
HDMT	histone demethylase
HIF	hypoxia Inducible factor
hMSCs	human mesenchymal stem cells
HO-1	heme oxygenase 1
HSP90B	heat shock protein 90-beta
HT	hydroxytyrosol
HTM	histone methyltransferase
IKK	ikappaB kinase
IL	interleuquin
iNOS	inducible nitric oxyde synthase
JNK	jun N-terminal kinase
lncRNA	long non-coding RNA
LPS	lipopolysaccharides
MAPK	mitogen-activated protein kinases
MIA	monosodium iodoacetate
miRNA	microRNA
MMP	metalloproteinase
NF-ĸB	nuclear factor kappa-light-chain-enhancer of activated B cells
NLRP3	nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3
NO	nitric oxide
NOS	nitric oxide synthase
NRF2	nuclear factor erythroid 2–related factor 2
NSAID	non-steroidal anti-inflammatory drugs
OA	osteoarthritis
OAC	OA chondrocyte
OARSI	osteoarthritis research society international
OCN	osteocalcin
OPN	osteopontin
OSM	oncostatin M
PARP	poly-ADP ribose polymerase
PG	proteoglycan
PGE2	prostaglandin E2
PPAR-γ	peroxisome proliferator-activated receptor gamma
PTEN	phosphatase and tensin homolog
PUFA	polyunsaturated fatty acids
RANKL	receptor activator of nuclear factor kappa beta ligand
RES	resveratrol
ROS	Reactive oxygen species
RUNX2	receptor activator of nuclear factor kappa-Β ligand
SIRT	sirtuin
SOST	sclerostin
SOX9	SRY-Box Transcription Factor 9
SSD	saikosaponin D
STAT	signal transducer and activator of transcription
TGF-β1	transforming growth factor beta-1
TIMP	tissue inhibitor of metalloproteinase
TLR4	toll-like receptor 4
TNF-α	tumoral necrosis factor alpha
VAS	visual analog scale
VEGF	vascular endothelial growth factor
WOMAC	Western Ontario and McMaster Universities Arthritis Index