Table 3.
Different tumor-to-brain ratios and the methodology used to obtain them.
| Parameter | Definition |
|---|---|
| TBRmean | Mean uptake in the tumor area with a TBR ≥ 1.6 divided by mean uptake in the normal brain |
| TBRmax | Maximal uptake in the tumor area divided by mean uptake in the normal brain |
| TBR10/16mm | Mean uptake in a ROI/VOI with a diameter of 10/16 mm centered on the tumor area with the highest uptake divided by mean uptake in the normal brain |
| TBR25mm2 | Mean uptake in a standardized ROI/VOI with a size of 25 mm2 placed manually at the biopsy sites centered to the titanium pellets on postoperative images divided by mean uptake in the normal brain |
| TBR3SD | Mean uptake in an isocontour region around the lesion maximum using a cutoff of three standard deviations above average activity in the reference region divided by mean uptake in the normal brain |
| TBR70/80% | Mean in a 70/80% isocontour region divided by mean uptake in the normal brain |
| TBR | Uptake in the tumor area (unspecified) divided by mean uptake in the normal brain |
| SUVmax/mean/BG | SUVmax/mean of the tumor area divided by maximal uptake in the normal brain |