Figure 2.
Percentage of receptor-specific radioligand uptake after 1 h incubation at 37 °C in PC-3 cells, comprising internalized (solid bars on the bottom) and membrane-bound fractions (checkered bars on top) corresponding to [99mTc]Tc-DT11 (NTS1R-specific: light blue bars on the left), (GRPR-specific: light pink bars in the middle, [36]), and [99mTc]Tc-DT11+[99mTc]Tc-DB7 (NTS1R+GRPR-specific: violet bars on the right); results represent mean values ± sd, n = 3 (each in triplicate) statistically significant differences are denoted with ****, correspond to p < 0.0001.