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. 2024 Sep 19;16(9):1223. doi: 10.3390/pharmaceutics16091223

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Selected biodistribution data of [^99mTc]Tc-DT11 (average %IA/g ± sd at 4 h pi) in PC-3 xenograft-bearing SCID mice; for comparison purposes, bars from left to right in each set correspond to block (animals co-injected excess NT (100 µg), n = 3; first bar: gray with square filling), controls (second bar: light blue, n = 4) and Entresto^® (mice orally receiving Entresto^® 30 min before injection of the radioligand, n = 4; third bar: dark blue). Values are shown for kidneys, intestines, pancreases and PC-3 tumors; statistically significant differences are denoted: **, for p < 0.01 and ****, for p < 0.0001.