Figure 2.

Multiple sequence alignment of the TkHMGR proteins. The secondary structural elements predicted with TkHMGR1 are shown above. Red box, white character represents strict identity; red character represents similarity in a group; blue frame represents similarity across groups. The η symbol refers to 3₁₀-helixs; α-helixs and 3₁₀-helixs are displayed as medium and small squiggles, respectively. β-strands are rendered as arrows; strict β-turns are denoted as TT letters. The orange line represents three different transmembrane helices. The blue and green boxes represent two HMG-CoA binding sites and two NADP(H) binding sites, respectively.