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Perturbation of Thioredoxin Reductase activity by the gold compounds in NSCLC cell lines. Lysates of H522 and A549 were collected after 24 h of treatment at 5 μM concentration. Assay performed with the Thioredoxin Reductase Assay Kit (Colorimetric) (ab83463). (A) Absolute Thioredoxin reductase (TrxR) activity normalized by the total milligrams of protein lysates. (B) Mean difference TrxR activity (%) relative to the vehicle (veh) of each time point.
