HER-2	Human epidermal growth factor receptor-2
Trast	Trastuzumab
GFB	Gefitinib
LCH	Lycorine hydrochloride
TPGS-COOH	Activated D-Alpha-Tocopheryl polyethylene glycol 1000 succinate
DSDL	Dual surface-decorated liposomes
PS	Particle size
PDI	Polydispersity index
ZP	Zeta potential
IC-50	Half-maximum inhibitory concentration
SDL	Single decorated liposomes
CLSM	Confocal laser scanning microscopy
ErbB-2	Erythroblastic leukemia viral oncogene homolog-2
RGDK	Cryptic CendR motif
NRP-1	Neuropilin-1
TCRP1	Tongue cancer resistance-associated protein
Akt	Protein kinase B
mTOR	Mammalian target of rapamycin
BCS	Biopharmaceutical classification system
MAPK/PI3K	Mitogen-activated protein kinase/phosphatidylinositol 3-kinase
TME	Tumor microenvironment
TPGS	D-Alpha-Tocopheryl polyethylene glycol 1000 succinate
HLB	Hydrophilic and lipophilic balance
FDA	Food and drug administration
DSPE-PEG2000	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000]
CAFs	Cancer-associated fibroblasts
ECM	Extracellular matrix
TAMs	Tumor-associated macrophages
MDSCs	Myeloid-derived suppressor cells
TGF-β	Transforming growth factor beta
VEGF	Vascular endothelial growth factor
TILs	Tumor-infiltrating lymphocytes
HIFs	Hypoxia-inducible factors
PD-L1	Programmed-death ligand
CTLA-4	Cytotoxic T-lymphocyte-associated protein-4
NKG-2A	Natural killer group 2A
EDC	1-Ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride
NHS	N-hydroxy succinimide
DMAP	4-(Dimethyl amino) pyridine
MTT	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
DAPI	4′,6-diamidino-2-phenylindole dihydrochloride
DMEM	Dulbecco’s Modified Eagle Medium
FBS	Fetal bovine serum
DCM	Dichloromethane
PBS	Phosphate buffered saline
RSM	Response surface methodology
DOE	Design of experiments
BBD	Box–Behnken design
R2	Correlation coefficient
RMSE	Root mean square error
SEM	Scanning electron microscopy
TEM	Transmission electron microscopy
XRD	X-ray diffraction
FTIR	Fourier transform infrared spectroscopy
EE	Entrapment efficiency
DL	Drug loading
RP-HPLC	Reverse-phase high-performance liquid chromatography
ICH	International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use
ACN	Acetonitrile
TFA	Trifluoroacetic acid
NCCS	National Centre for Cell Science
DMSO	Dimethyl sulfoxide
CLSM	Confocal laser scanning microscopy
MFI	Mean fluorescence intensity