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Different levels of independent variables (3 factors and 3 levels) by using BBD for optimization of TPGS-based liposomes.
| Variables | Levels | ||
|---|---|---|---|
| −1 | 0 | +1 | |
| Independent variables | |||
| X1 = E-80 (mg) | 30 | 45 | 60 |
| X2 = Cholesterol (mg) | 10 | 15 | 20 |
| X3 = TPGS (mg) | 5 | 7.5 | 10 |
| Dependent variables | Desired response | ||
| Y1 = PS (nm) | Minimum | ||
| Y2 = PDI | Minimum Maximum |
||
| Y3 = ZP (±) | |||
