Table 2.

Total number of formulations generated by BBD representing the value of independent variables (E-80, cholesterol, and TPGS) and their corresponding values of dependent variables (PS, PDI, and ZP).

Independent Variable (Factors)				Dependent Variable (Response)
Formulation Code	Factor 1 (X1)	Factor 2 (X2)	Factor 3 (X3)	PS (nm) Y1	PDI Y2	ZP (±mV) Y3
LP1	45	15	7.5	152.8 ± 1.54	0.375 ± 0.046	−7.36
LP 2	60	15	5	189.4 ± 2.06	0.423 ± 0.068	−11.32
LP 3	30	15	5	135.5 ± 1.36	0.355 ± 0.034	−9.1
LP 4	30	15	10	143.5 ± 1.48	0.362 ± 0.081	−6.31
LP 5	30	20	7.5	149.2 ± 1.59	0.348 ± 0.059	−8.26
LP 6	45	20	5	164.3 ± 1.85	0.318 ± 0.047	−9.69
LP 7	60	15	10	194.6 ± 2.18	0.463 ± 0.065	−9.2
LP 8	60	10	7.5	180.6 ± 2.03	0.494 ± 0.072	−10.3
LP 9	45	10	5	147.9 ± 1.47	0.395 ± 0.061	−8.19
LP 10	45	15	7.5	152.8 ± 1.54	0.375 ± 0.058	−7.669
LP 11	30	10	7.5	114.7 ± 1.16	0.385 ± 0.055	−8.88
LP 12	45	10	10	151.1 ± 1.54	0.378 ± 0.053	−6.8
LP 13	45	15	7.5	152.8 ± 1.54	0.375 ± 0.062	−7.36
LP 14	45	20	10	183.6 ± 1.97	0.325 ± 0.048	−9.16
LP 15	60	20	7.5	198.4 ± 2.38	0.338 ± 0.056	−15.62