Table 3.
Analyses within dataset/study 1 and 2, with corresponding statical test and outcome details.
| Dataset 1: Longitudinal NLR and Sedation Rate | ||||||
|---|---|---|---|---|---|---|
| Analysis Description | Statistical Test | Sample | Independent Variable(s) | Dependent Variable | Covariate(s) | Result(s) |
| 1a. Longitudinal NLR | Repeated Measures ANCOVA | Non-study baboons with NLR years 1 through 5, N = 174 | Sex, rearing | lg10NLR years 1–5 | Most recent age | Significant effect of time; pairwise comparisons: no differences between years |
| 1b. Cross-sectional age and NLR | Curve estimation | Non-study baboons, N = 472 | Most recent age | Most recent lg10NLR | Significant quadratic and linear relationship | |
| 2a. NLR and assignment to study, sedation rate | Linear regression | The entire sample (including study baboons), N = 532 | Sex, rearing, and age at the most recent NLR on the first block | Most recent lg10NLR | Age and rearing significant predictors—see Table 3 for coefficients | |
| Assignment to study on the second block | n.s. | |||||
| Sedation rate on the last block | Significant negative relationship | |||||
| 2b. NLR and sedation rate using a matched sample | Linear regression | Baboons matched with study baboons on age, sex, and rearing, N = 131 (66 study and 65 non-study) | Sex and rearing on the first block | Most recent lg10NLR | Replicated result 2a | |
| Assignment to study on the second block | Replicated result 2a | |||||
| Sedation rate on the last block | Replicated result 2a | |||||
| 2c. NLR change over time as a function of sedation rate | Linear regression | Non-study baboons with a minimum of 24 months between timepoints, N = 237 | Sex, rearing, and most recent age on the first block | Change score (normally distributed) | Sex and age were significant predictors of NLR change scores. | |
| Sedation rate on the last block | n.s. | |||||
| Dataset 2: NLR and Sedation Order, Health Parameters | ||||||
| 3. NLR and sedation order | Linear regression | Entire sample, N = 231 | Sex, rearing, and age on the first block | lg10NLR | Sex and rearing were significant predictors | |
| Sedation order on the second block | Sedation order was a significant predictor | |||||
| 4. NLR and injury | Univariate ANCOVA | Entire sample, N = 231 | Sex, rearing | lg10NLR | Age | The main effects of sex and rearing were significant |
| Injury (y/n) | Injury n.s., but trending injury by sex interaction | |||||
| 5. NLR, pregnancy, dependent infant | Univariate ANCOVA | Adult females only, N = 112 | Rearing | lg10NLR | Age | The main effect of rearing was significant |
| Pregnancy (y/n) | n.s. | |||||
| Dependent infant (present/absent) | Trending infant by rearing interaction | |||||
Note: n.s.: not significant.