Table 1.

Distribution of TCDD, TrBDF, TeBDF, PeBDF, and TrBCDF in the liver, plasma, and brain of exposed mice (as fractions of the administered doses).

Compound	Day	Liver	Plasma 1	Brain
TCDD	1	0.69	3.3 × 10−3	3.6 × 10−3
	3	0.84	2.4 × 10−3	1.8 × 10−3
	7	0.73	1.5 × 10−3	1.4 × 10−3
	28	0.16	4.8 × 10−4	3.4 × 10−4
	56	0.012	2.7 × 10−4	1.2 × 10−4
TrBDF	1	8.0 × 10−5	9.6 × 10−6	1.1 × 10−5
	3	9.1 × 10−6	1.4 × 10−6	1.1 × 10−6
	7	2.3 × 10−6	4.1 × 10−7	3.7 × 10−7
	28	7.9 × 10−7	ND 2	ND 2
TrBCDF	1	0.42	1.7 × 10−3	3.4 × 10−4
	3	0.24	3.5 × 10−4	7.2 × 10−5
	7	0.23	1.4 × 10−4	4.5 × 10−5
	28	0.015	7.4 × 10−5	7.5 × 10−6
TeBDF	1	0.33	1.7 × 10−3	1.9 × 10−4
	3	0.31	3.8 × 10−4	5.0 × 10−5
	7	0.26	2.8 × 10−4	3.0 × 10−5
	28	0.053	1.1 × 10−4	1.1 × 10−5
	56	5.2 × 10−3	3.2 × 10−5	6.4 × 10−6
PeBDF	1	0.29	5.4 × 10−4	3.6 × 10−5
	3	0.25	9.9 × 10−5	6.5 × 10−6
	7	0.27	6.9 × 10−5	3.7 × 10−6
	28	0.085	2.6 × 10−5	7.1 × 10−7

¹ calculated from plasma concentrations assuming a plasma/body weight ratio of 6% for mouse [42]; ² not detected