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. 2024 Aug 26;12(9):963. doi: 10.3390/vaccines12090963

Figure 2.

Figure 2

Neutralizing antibody titers of SPF mini pigs at 8 weeks post-vaccination (Exp 1). (a) VN titers against the A/Iraq/24/64 strain by each group: G1, (no adjuvant), G2 (ISA 206), G3 (ISA 201), G4 (ISA 207), G5 (Emulsigen-D), G6 (Emulsigen-D with Al(OH)3), G7 (Al(OH)3), G8 (IMS1313), G9 (Gel). (b) VN titers against A/Iraq/24/64 strain in each category. W/O/W adjuvant (G2, ISA 206; G3, ISA 201; G4, ISA 207), O/W adjuvant (G5, Emulsigen-D; G6, Emulsigen-D with Al(OH)3), polymer nanomaterials (G7, Al(OH)3; G8, IMS1313; G9, GEL 01). (b) VN titers against the A/Iraq/24/64 strain categorized by adjuvant types. VN titers ≥ 1.65 log10 (dotted line) are considered positive for FMDV antibodies. G, group; ID, intradermal; SPF, specific pathogen-free; W/O/W/, water-in-oil-in-water emulsion vaccines; O/W, oil-in-water emulsion vaccines; wpv, weeks post-vaccination; the datasheets are the mean ± SEM; statistical analyses were performed using one-way ANOVA; * p < 0.05; ** p < 0.01.