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. 2024 Sep 10;12(9):662. doi: 10.3390/toxics12090662

Table 3.

Treatment for all patients and in selected substance classes.

Treatment All
n = 872
All Opiates
and Opioids
n = 499
p BZD and
Z-Drugs
n = 467
p Cathinones and PA
n = 70
p SCRA
n = 53
p
Treatment Yes 846 (97.0%) 492 (98.6%) 0.002 * 461 (98.7%) 0.002 * 69 (98.6%) 0.426 46 (86.8%) <0.001 *
No 26 (3.0%) 7 (1.4%) 6 (1.3%) 1 (1.4%) 7 (13.2%)
Intubation Pre-hospital 37 (4.2%) 25 (5.0%) 0.057 21 (4.5%) 0.723 3 (4.3%) 0.304 1 (1.9%) 0.694
Hospital 24 (2.8%) 17 (3.4%) 13 (2.8%) 4 (5.7%) 2 (3.8%)
No 811 (93.0%) 457 (91.6%) 433 (92.7%) 63 (90.0%) 50 (94.3%)
Naloxone Pre-hospital 44 (5.0%) 39 (7.8%) <0.001 * 26 (5.6%) 0.011 * 2 (2.9%) 0.638 0 (0%) 0.011
Hospital 38 (4.4%) 32 (6.4%) 29 (6.2%) 4 (5.7%) 0 (0%)
Both 7 (0.8%) 7 (1.4%) 4 (0.9%) 0 (0%) 0 (0%)
No 783 (89.8%) 421 (84.4%) 408 (87.4%) 64 (91.4%) 53 (100%)
Flumazenil Pre-hospital 18 (2.1%) 13 (2.6%) 0.002 * 14 (3.0%) <0.001 * 0 (0%) 0.878 0 (0%) 0.076
Hospital 28 (3.2%) 23 (4.6%) 24 (5.1%) 4 (5.8%) 0 (0%)
Both 1 (0.1%) 1 (0.2%) 1 (0.2%) 0 (0%) 0 (0%)
No 824 (94.5%) 462 (92.6%) 428 (91.6%) 65 (94.2%) 52 (100%)
Sedation Pre-hospital 53 (6.1%) 22 (4.4%) <0.001 * 11 (2.4%) <0.001 * 5 (7.1%) <0.001 * 10 (18.9%) <0.001 *
Hospital 219 (25.1%) 90 (18.1%) 95 (20.3%) 27 (38.6%) 9 (17.0%)
Both 70 (8.0%) 30 (6.0%) 27 (5.8%) 11 (15.7%) 3 (5.7%)
No 529 (60.7%) 356 (71.5%) 334 (71.5%) 27 (38.6%) 31 (58.5%)

BZD = benzodiazepines, PA = Phenethylamines. Bold * = p < 0.05