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. 2024 Aug 28;25(10):1830–1844. doi: 10.1038/s41590-024-01918-6

Table 1.

Breast cancer patient clinical information

Patient no. Sample type Na+ (g kg−1) K+ (g kg−1) Sex Tumor status Nodal status Metastasis Grading Stage according to UICC Estrogen receptor (%) Progesterone receptor (%) Her2 status Histological classification Localization of breast tumor Neoadjuvant therapy
1 Lesional tumor 2.18 3.34 F pT1c, pTis (DCIS, non-high-grade with necrosis—intermediate malign) pN0 (sn), (0/2) MX G2 IV 100 90 2+ (FISH negative) Ductal Right No
2 Perilesional tissue 3.22 1.89
3 Lesional tumor 4.98 4.27 F pT1c (m), pTis pN1a (1/13) cM0 G2 IIA 95 70 Negative (DAKO-score 1+) Lobular Left No
4 Perilesional tissue 0.735 0.337
5 Lesional tumor 9.34 4.49 F pT4b pN2a (8/10) MX G1 IV 90 2+ (positiv). Ductal Left No
6 Perilesional tissue 2.46 0.905
7 Lesional tumor 4.74 6.18 F pT1c pN(sn)0 (0/2) MX G2, BRE-score: 6 (2 + 1 + 3) IV 100 2 2+ (FISH negative) Ductal Left No
8 Perilesional tissue 2.76 0.978
9 Lesional tumor 8.52 2.21 F pT1c pN(sn)0 (0/3) MX G1 IV 10 100 2+ (FISH negative) Mucinous Left No
10 Perilesional tissue 0.464 0.207
11 Lesional tumor 6.54 11.7 F pT2 pN1 (1/9) MX G2, BRE-score: 7 (1 + 3 + 3) IV 100 70 Negative Ductal Right No
12 Perilesional tissue
13 Lesional tumor 6.04 9.08 F pT2 pN0 (sn) (0/2) MX G2 IV 100 95 Negative (score 1+) Ductal Right No
14 Perilesional tissue 1.74 0.91
15 Lesional tumor 6.25 10 F pT1c pN(sn)0 (0/2) cM0 G3, BRE-score 9 I Negative Negative 2+ (FISH negative) Ductal Left No
16 Perilesional tissue 1.96 0.823
17 Lesional tumor 5.69 11.7 F pT1c(m), pTis pN0sn (0/5) cM0 G2 (invasive component), WHO grade II (DCIS) I 90% positive in the invasive carcinoma, 90% in the in situ component Positive (80%) invasive carcinoma, 20% in situ component 2+ (FISH negative) Ductal Left No
18 Perilesional tissue 8.63 4.07
19 Lesional tumor 7.32 7.83 F pT4b pN2a (7/7) MX G3, BRE-score: 8 (3 + 3 + 2) IV Negative Negative 2+ (FISH negative) Ductal Right No
20 Perilesional tissue 4.52 1.32

cM0, no cancer spread; DCIS, ductal cancer in situ; F, female; MX, distant metastasis; UICC, Union for International Cancer Control.