Table 1.
Multivariable Cox regression analysis
| Variables | Overall survival | Cancer-specific survival | Recurrence-free survival | Progression-free survival | ||||
|---|---|---|---|---|---|---|---|---|
| HR (95%CI) | p value | HR (95%CI) | p value | HR (95%CI) | p value | HR (95%CI) | p value | |
| Age | ||||||||
| Group 2 (> 70y) | Ref | Ref | Ref | Ref | ||||
| Group 1 (< = 70y) | 0.29 (0.25–0.35) | < 0.001 | 0.51 (0.36–0.72) | < 0.001 | 0.82 (0.71–0.95) | < 0.01 | 1.09 (0.82–1.45) | 0.55 |
| Adequate BCG | ||||||||
| No | Ref | Ref | Ref | Ref | ||||
| Yes | 0.78 (0.68–0.88) | < 0.001 | 0.63 (0.46–0.85) | < 0.01 | 0.81 (0.70–0.92) | < 0.01 | 0.55 (0.41–0.72) | < 0.001 |
| Gender | ||||||||
| Female | Ref | Ref | Ref | Ref | ||||
| Male | 1.35 (1.14–1.58) | < 0.001 | 1.04 (0.73–1.49) | 0.93 | 1.24 (1.04–1.47) | 0.02 | 1.91 (1.29–2.85) | < 0.01 |
| Charlson Comorbidity Index | ||||||||
| 2 | Ref | Ref | Ref | Ref | ||||
| 3 | 1.46 (1.25–1.71) | < 0.001 | 0.99 (0.68–1.43) | 0.94 | 1.03 (0.87–1.21) | 0.77 | 0.81 (0.57–1.15) | 0.24 |
| 4 | 2.08 (1.69–2.57) | < 0.001 | 1.17 (0.69–1.99) | 0.55 | 0.95 (0.74–1.21) | 0.67 | 0.91 (0.55–1.50) | 0.71 |
| 5–10 | 2.72 (2.17–3.40) | < 0.001 | 1.22 (0.65–2.29) | 0.54 | 1.04 (0.78–1.38) | 0.82 | 0.83 (0.44–1.58) | 0.57 |
| Hypertension | ||||||||
| No | Ref | Ref | Ref | Ref | ||||
| Yes | 1.02 (0.88–1.18) | 0.81 | 1.16 (0.83–1.62) | 0.40 | 1.18 (1.01–1.38) | 0.04 | 0.99 (0.73–1.35) | 0.96 |
| Hyperlipidemia | ||||||||
| No | Ref | Ref | Ref | Ref | ||||
| Yes | 0.70 (0.60–0.83) | < 0.001 | 0.69 (0.46–1.04) | 0.08 | 0.88 (0.74–1.05) | 0.16 | 0.79 (0.54–1.16) | 0.23 |