FIG. 2.

VV undergoes only limited replication in keratinocytes, while replicating robustly in dermal fibroblasts and endothelial cells. Primary cultures of the indicated skin cells were infected with WR-VV at an MOI of 0.1 (0.1 PFU per cell). Sixty hours later, the numbers of virus particles in the cultures were determined by plaque assay and are shown as PFU per input cell. This is a representative result of three independent experiments.