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. 2024 Jul 13;40(4):639–651. doi: 10.1007/s43188-024-00253-0

Table 1.

Serum biochemical analyses of TCP–treated SD rats

Category Vehicle LoTCP HiTCP
ALT (U/L) 60.7 ± 8.36 87.2 ± 14.7 120.3 ± 23.28*
AST (U/L) 78.1 ± 8.50 100 ± 15.4 150.4 ± 58.05*
ALP (g/mL) 511.9 ± 82.03 685.56 ± 108.69 647 ± 110.20
BUN (mg/dL) 19.86 ± 1.73 20.48 ± 2.03 22.26 ± 3.12

Serum biochemical analysis for the hepatotoxicity indicators. The ALT, AST, ALP, and BUN concentrations in the serum were analyzed using a serum biochemical analyzer. The whole blood samples were prepared from five to seven rats per group, and serum biochemical analyses were performed twice for each sample. The data are reported as the mean ± SD

TCP 1,2,3-Trichloropropane, LoTCP Low concentration of TCP, HiTCP High concentration of TCP, AST aspartate aminotransferase, ALP Alkaline phosphatase, BUN Blood urea nitrogen

*p < 0.05 compared with the Vehicle-treated group