FIG. 4.

CD80 expression continues to increase only on C57BL/6 BMDC between 24 and 48 h postinfection with rSV5. Day 7 BMDC from both strains of mice were mock infected, treated with LPS, or infected with rSV5 (MOI = 10) for 24 h or 48 h. Cells were then stained with antibodies to CD11c and CD80 and analyzed by flow cytometry. The graphs in the figure show the geometric mean fluorescent intensity of CD80 for CD11c⁺ cells for both C57BL/6 (A) and BALB/c (B) BMDC. The graphs show the average ± standard error of the mean of four independent experiments. P values were calculated using the paired t test. *, upregulation of CD80 on C57BL/6 BMDC following infection with rSV5 compared to mock-infected BMDC was statistically significant (24 h: P = 0.024; 48 h: P = 0.040).