FIG. 3.

Characterization of CD4 and CD8 epitope responses of BALB/c mice to HIV Gag. BALB/c mice were injected with the indicated vectors encoding Gag as described in Materials and Methods, and ICS to the indicated pairs of peptides was determined. The peptides to the HIV Gag region were synthesized as 15-mers overlapping by 11 (16, 17). Responses to the (A) CD4 or (B) CD8 epitopes are shown. The minimal threshold response is indicated by the dashed line. Red, blue, and black bars are as defined in the legend to Fig. 1.