Timing of administration of rotavirus vaccines in association with age-related changes in titres of maternal serum and breastmilk antibodies and infant serum IgG and IgA titres. Neonatal vaccine schedule (first dose at birth) (red arrows) with RV3-BB vaccine; infant vaccine schedule (first dose at 6–8 weeks of age) (black arrows): WHO-prequalified rotavirus vaccines (Rotarix®, RotaTeq®, Rotavac® (Bharat Biotech, Hyderabad, India) and Rotasiil® (Serum Institute of India, Pune, India) and RV3-BB vaccine administered in the infant schedule). Adapted from: Otero CE, Langel SN, Blasi M, Permar SR. PLoS Pathogens 2020 16(11):e1009010 [8].