Table 2.
Occurrence of Oropouche Virus (i.e., detection of either virus isolates or RNA) from samples collected from subjects with any sign/symptom of arbovirus infection.
| Total Samples (N) | OROV-Positive Cases (n/N, %) | Risk Ratio (95%CI) | |
|---|---|---|---|
| Overall | 32,439 | 532, 1.64% | - |
| Timeframe | |||
| Before 1990 | 344 | 92, 26.74% | REFERENCE |
| 1991–2010 | 21,178 | 19, 0.09% | 0.003 (0.002; 0.005) |
| After 2010 | 10,917 | 421, 3.86% | 0.144 (0.118; 0.175) |
| Country | |||
| Bolivia | 2089 | 0, - | 0.006 (0.001; 0.096) |
| Brazil | 4030 | 162, 4.02% | REFERENCE |
| Colombia | 3067 | 105, 3.42% | 0.852 (0.669; 1.084) |
| Ecuador | 579 | 0, - | 0.021 (0.001; 0.344) |
| French Guyana | 95 | 23, 24.21% | 6.023 (4.092; 8.864) |
| Haiti | 1250 | 1, 0.08% | 0.020 (0.003; 0.142) |
| Paraguay | 340 | 0, - | 0.037 (0.002; 0.586) |
| Peru | 20,989 | 241, 1.15% | 0.286 (0.235; 0.348) |
| Sample | |||
| Blood | 32,152 | 525, 1.63% | REFERENCE |
| CSF | 287 | 7, 2.44% | 1.494 (0.715; 3.120) |
| Diagnostic procedure | |||
| Virus isolation | 946 | 138, 14.59% | 4.347 (3.612; 5.231) |
| RT-qPCR | 10,518 | 353, 3.36% | REFERENCE |
| RT-qPCR + IFAT | 20,880 | 18, 0.08% | 0.026 (0.016; 0.041) |
| RT-qPCR + MNT | 95 | 23, 24.21% | 7.214 (4.981; 10.446) |
Note: OROV = Oropouche Virus; 95%CI = 95% confidence interval; RT-qPCR = real-time polymerase chain reaction; CSF = cerebrospinal fluid; IFAT = indirect immunofluorescence assay; MNT = microneutralization test.