Table 3.
Comparison of the optical coherence tomography angiography parameters in the superficial capillary plexus in circumpapillary vasculature
| OCTA parameters | Unaffected fellow eye (n = 30) |
Control (n = 31) |
||
|---|---|---|---|---|
| Adjusted mean (standard error) | p-value | |||
| Inner | VD (mm-1) | |||
| Average | 16.53 (0.35) | 15.94 (0.35) | 0.247 | |
| Superior | 17.48 (0.40) | 17.62 (0.40) | 0.811 | |
| Temporal | 14.07 (0.89) | 13.36 (0.89) | 0.585 | |
| Inferior | 16.05 (0.56) | 17.12 (0.55) | 0.020* | |
| Nasal | 17.28 (0.34) | 17.63 (0.34) | 0.482 | |
| PD (%) | ||||
| Average | 43.80 (0.96) | 41.98 (0.92) | 0.181 | |
| Superior | 45.60 (1.44) | 46.96 (1.43) | 0.515 | |
| Temporal | 33.99 (2.25) | 32.23 (2.23) | 0.591 | |
| Inferior | 43.96 (1.44) | 44.98 (1.44) | 0.006* | |
| Nasal | 46.18 (0.84) | 46.63 (0.84) | 0.713 | |
| Outer | VD (mm-1) | |||
| Average | 17.11 (0.27) | 18.60 (0.27) | < 0.001* | |
| Superior | 17.58 (0.42) | 18.05 (0.41) | 0.437 | |
| Temporal | 18.46 (0.40) | 19.89 (0.40) | 0.017* | |
| Inferior | 17.00 (0.34) | 18.91 (0.33) | < 0.001* | |
| Nasal | 15.05 (0.42) | 17.46 (0.42) | < 0.001* | |
| PD (%) | ||||
| Average | 42.76 (0.74) | 47.07 (0.74) | < 0.001* | |
| Superior | 46.16 (1.06) | 46.72 (1.05) | 0.718 | |
| Temporal | 44.76 (1.04) | 48.39 (1.04) | 0.019* | |
| Inferior | 42.26 (1.14) | 48.78 (1.13) | < 0.001* | |
| Nasal | 36.84 (1.24) | 44.10 (1.23) | < 0.001* | |
| Total | VD (mm-1) | 16.60 (0.23) | 17.54 (0.23) | < 0.001* |
| PD (%) | 42.10 (0.63) | 44.70 (0.63) | < 0.001* | |
OCTA = optical coherence tomography angiography; PD = perfusion density; center = circular area with 0.5 mm for its radius centered on Bruch’s membrane opening (BMO); inner = ring-shaped area about 0.5–1.5 mm centered on BMO; outer = ring-shaped area about 1.5–3.0 mm centered on BMO; total = circular area with 3 mm for its radius centered on BMO
P-value calculated by analysis of covariance to compare between two groups adjusted for age, sex, axial length; *p-value < 0.05