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. 2024 Sep 27;24:421. doi: 10.1186/s12886-024-03686-1

Table 4.

Comparison of the optical coherence tomography angiography parameters in the superficial capillary plexus in macular vasculature

OCTA parameters Unaffected fellow eye
(n = 30)
Control
(n = 31)
Adjusted mean (standard error) p-value
Center VD (mm-1) 7.87 (0.54) 10.31 (0.53) 0.002*
PD (%) 18.07 (1.26) 23.20 (1.24) 0.006*
Inner VD (mm-1)
Average 16.89 (0.31) 18.31 (0.30) 0.002*
Superior 16.81 (0.35) 18.31 (0.35) 0.004*
Temporal 16.31 (0.47) 18.11 (0.46) 0.010*
Inferior 17.18 (0.33) 18.58 (0.33) 0.005*
Nasal 17.26 (0.28) 18.26 (0.28) 0.017*
PD (%)
Average 40.26 (0.82) 43.72 (0.80) 0.004*
Superior 40.05 (1.14) 43.46 (1.12) 0.041*
Temporal 39.10 (1.19) 43.09 (1.17) 0.023*
Inferior 41.28 (0.86) 45.03 (0.85) 0.004*
Nasal 40.59 (0.75) 43.31 (0.73) 0.014*
Outer VD (mm-1)
Average 16.62 (0.31) 18.35 (0.30) < 0.001*
Superior 16.63 (0.36) 18.28 (0.36) 0.002*
Temporal 15.25 (0.48) 17.27 (0.47) 0.005*
Inferior 16.15 (0.42) 18.46 (0.41) < 0.001*
Nasal 18.45 (0.27) 19.39 (0.26) 0.016*
PD (%)
Average 40.67 (0.93) 44.83 (0.91) 0.003*
Superior 40.11 (1.38) 44.53 (1.35) 0.029*
Temporal 37.03 (1.28) 42.52 (1.25) 0.004*
Inferior 40.06 (1.08) 46.39 (1.06) < 0.001*
Nasal 45.24 (0.75) 47.30 (0.74) 0.059
Total VD (mm-1) 16.40 (0.30) 18.12 (0.29) < 0.001*
PD (%) 40.39 (0.89) 44.15 (0.87) 0.005*
FAZ Area (mm2) 0.27 (0.03) 0.27 (0.03) 0.995
Perimeter (mm) 2.19 (0.12) 2.14 (0.84) 0.808
Circularity 0.67 (0.08) 0.73 (0.11) 0.037*

OCTA = optical coherence tomography angiography; VD = vessel density; PD = perfusion density; FAZ = foveal avascular zone; center = circular area with 0.5 mm for its radius centered on fovea; inner = ring-shaped area about 0.5–1.5 mm centered on fovea; outer = ring-shaped area about 1.5–3.0 mm centered on fovea; total = circular area with 3 mm for its radius centered on fovea

P-value calculated by analysis of covariance to compare between two groups adjusted for age, sex, axial length; *p-value < 0.05