Table 4.
Comparison of the optical coherence tomography angiography parameters in the superficial capillary plexus in macular vasculature
| OCTA parameters | Unaffected fellow eye (n = 30) |
Control (n = 31) |
||
|---|---|---|---|---|
| Adjusted mean (standard error) | p-value | |||
| Center | VD (mm-1) | 7.87 (0.54) | 10.31 (0.53) | 0.002* |
| PD (%) | 18.07 (1.26) | 23.20 (1.24) | 0.006* | |
| Inner | VD (mm-1) | |||
| Average | 16.89 (0.31) | 18.31 (0.30) | 0.002* | |
| Superior | 16.81 (0.35) | 18.31 (0.35) | 0.004* | |
| Temporal | 16.31 (0.47) | 18.11 (0.46) | 0.010* | |
| Inferior | 17.18 (0.33) | 18.58 (0.33) | 0.005* | |
| Nasal | 17.26 (0.28) | 18.26 (0.28) | 0.017* | |
| PD (%) | ||||
| Average | 40.26 (0.82) | 43.72 (0.80) | 0.004* | |
| Superior | 40.05 (1.14) | 43.46 (1.12) | 0.041* | |
| Temporal | 39.10 (1.19) | 43.09 (1.17) | 0.023* | |
| Inferior | 41.28 (0.86) | 45.03 (0.85) | 0.004* | |
| Nasal | 40.59 (0.75) | 43.31 (0.73) | 0.014* | |
| Outer | VD (mm-1) | |||
| Average | 16.62 (0.31) | 18.35 (0.30) | < 0.001* | |
| Superior | 16.63 (0.36) | 18.28 (0.36) | 0.002* | |
| Temporal | 15.25 (0.48) | 17.27 (0.47) | 0.005* | |
| Inferior | 16.15 (0.42) | 18.46 (0.41) | < 0.001* | |
| Nasal | 18.45 (0.27) | 19.39 (0.26) | 0.016* | |
| PD (%) | ||||
| Average | 40.67 (0.93) | 44.83 (0.91) | 0.003* | |
| Superior | 40.11 (1.38) | 44.53 (1.35) | 0.029* | |
| Temporal | 37.03 (1.28) | 42.52 (1.25) | 0.004* | |
| Inferior | 40.06 (1.08) | 46.39 (1.06) | < 0.001* | |
| Nasal | 45.24 (0.75) | 47.30 (0.74) | 0.059 | |
| Total | VD (mm-1) | 16.40 (0.30) | 18.12 (0.29) | < 0.001* |
| PD (%) | 40.39 (0.89) | 44.15 (0.87) | 0.005* | |
| FAZ | Area (mm2) | 0.27 (0.03) | 0.27 (0.03) | 0.995 |
| Perimeter (mm) | 2.19 (0.12) | 2.14 (0.84) | 0.808 | |
| Circularity | 0.67 (0.08) | 0.73 (0.11) | 0.037* | |
OCTA = optical coherence tomography angiography; VD = vessel density; PD = perfusion density; FAZ = foveal avascular zone; center = circular area with 0.5 mm for its radius centered on fovea; inner = ring-shaped area about 0.5–1.5 mm centered on fovea; outer = ring-shaped area about 1.5–3.0 mm centered on fovea; total = circular area with 3 mm for its radius centered on fovea
P-value calculated by analysis of covariance to compare between two groups adjusted for age, sex, axial length; *p-value < 0.05