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. 2024 Jan 13;14(9):100937. doi: 10.1016/j.jpha.2024.01.005

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© 2024 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 1 — Fabrication and characterization of macrophage membrane (Møm)-coated rosuvastatin (RVS)-loaded Prussian blue (PB) nanoparticles (MPR NPs). (A, B) Transmission electron microscope (TEM) images of RVS-loaded PB NPs (PR NPs) (A) and MPR NPs (B) (inset: magnified MPR NPs image). (C) Dynamic light scattering (DLS) analysis of PB NPs, PR NPs, and MPR NPs. (D) Zeta potentials of PB NPs, PR NPs, and MPR NPs. (E) Coomassie brilliant blue stain analysis of Møm and MPR NPs proteins. (F) Western blot assay of characteristic marker cluster of differentiation 11b (CD11b) in the Møm and MPR NPs. (G) Fluorescence imaging of a mixture of Møm and PB NPs. (H) The effect of PB NPs and RVS with different proportions (2:1, 1:1, and 1:2) on encapsulation efficiency (EE)/loading efficiency (LE). (I) Fourier transform infrared spectroscopy (FT-IR) spectra of RVS and PR NPs, and the amplification of selected region. DiL: 1,1-dioctadecyl-3,3,3,3-tetramethylindocarbocyanine perchlorate; DiD: 1,1-dioctadecyl-3,3,3,3-tetramethylindodicarbocyanine perchlorate.