Table 2.
Characteristics of the included economic burden studies
| Study | Region | Study design | Research perspective | Sample size | Dementia type | Mean age (SD) |
Mean disease duration (SD) | Women (%) | Dementia severity classification criteria | Cost category (Mean) |
|---|---|---|---|---|---|---|---|---|---|---|
| Wang et al., 2008 [21] | Shanghai | Cross-sectional study | / | 66 | AD | 74.0 (8.6) | 2.7 (2.0) | 65.2 | MMSE |
Direct medical costs (5,640 RMB) Direct non-medical costs (2,792 RMB) Indirect costs (10,568 RMB) |
| Liu et al., 2009 [22] | Shanghai | Cross-sectional study | / | 63 |
AD VD Other |
78.5 (6.7) | 4.3 (2.9) | 82.5 | CDR |
Medical care costs (8,545.2 RMB) Caregiver economic loss (5,360.4 RMB) |
| Wang et al., 2012 [23] | Taiyuan | Cross-sectional study | societal | 168 | AD | / | / | 52.4 | CDR |
Direct medical costs (7,708 RMB) Direct non-medical costs (1,525 RMB) Indirect costs (6,516 RMB) |
| Deng et al., 2016 [24] | Guangzhou | Cross-sectional study | / | 77 |
AD VD Other |
77.3 (9.9) | 5.1 (3.2) | 63.6 | / |
Medical costs (9,902.4 RMB) Total nursing costs (10,766.4 RMB) Bed and meal costs (11,217.6 RMB) Transportation and lost work time costs (2,481.6 RMB) |
| Ku et al., 2016 [25] | Taiwan | Cross-sectional study | societal | 231 |
AD VD DLB Uncertain |
80.0 (6.9) | / | 59.7 | CDR or MMSE |
Medical costs (82,489 NT$) Social care costs (93,552 NT$) Informal care costs (116,285 NT$) |
| Yan et al., 2019 [26] | Multi-center | Cross-sectional study | / | 3046 | AD |
75.27 (9.40) |
/ | 54.2 | MMSE |
Direct medical costs (/) Direct non-medical costs (/) Indirect costs (/) intangible costs (/) |
| Huang et al., 2020 [27] | Jiangxi | Cross-sectional study | / | 76 | AD | 78.0 (5.0) | / | 40.8 | MMSE |
Direct medical costs (11,920 RMB) Direct non-medical costs (4,121 RMB) Indirect costs (25,047 RMB) |
| Wu et al., 2020 [28] | Guangzhou | Cross-sectional study | health economics | 157 |
AD VD MD FTD DLB Uncertain |
76.8 (10.0) |
/ | 59.2 | CDR |
Formal care costs (20,383 RMB) Informal care costs (45,402 RMB) |
AD Alzheimer's disease, VD vascular dementia, DLB dementia with Lewy bodies, FTD frontotemporal lobe dementia, MD mixed dementia, SD standard deviation, CDR Clinical Dementia Rating scale, MMSE Mini-Mental State Examination