Fig. 5.

Lipophagy contributes to cell growth. (A) shATG10 was used to inhibit lipophagy. (B) Blocking lipophagy significantly increased the accumulation of lipid droplets, as shown by Oil Red O staining. (C) Quantitative analysis of the Oil red O staining results. (D) Inhibition of lipophagy by shATG10 significantly induced cell death. (E) Quantitative analysis of the ratio of dead cells by calcein AM/PI staining. N = 4 for B and C. * indicates a P value lower than 0.05, which was determined by the Mann‒Whitney U test