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Comparison of activities of F12-Nef and its revertant proteins
| Nef alleles | Virus production | Gag processing | Virion infectivity | Perinuclear concn | p74/75 binding |
|---|---|---|---|---|---|
| NL4-3–Nef | + | + | + | − | − |
| F12-Nef | − | − | − | + | + |
| F12-Nef E140G | + | + | − | − | + |
| F12-Nef L153V | + | + | − | − | + |
| F12-Nef G177E | + | + | + | − | − |
