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Cryo-EM images of frozen-hydrated virions of reovirus T3D. (A) Native virions. An arrow indicates projections of ς3 on the outer capsid. (B) Virions bound by 4F2 IgG. An arrowhead indicates mass density due to IgG. (C) Virions bound by 4F2 Fabs. An arrowhead indicates mass density due to Fabs. All images were obtained at ×30,000 magnification using an electron dose of 5 electrons/Å2. Scale bar, 1,000 Å.
