. 2024 Sep 21;30(35):3996–4010. doi: 10.3748/wjg.v30.i35.3996

Table 2.

Impact of individual metabolic syndrome components on adverse clinical outcomes in hypertriglyceridemia-acute pancreatitis

Outcome	Obesity		Hyperglycaemia		Hypertension		Low HDL-C
Outcome	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Pleural effusion	1.52 (0.89-2.61)	0.129	1.75 (0.88-3.46)	0.109	1.12 (0.69-1.84)	0.644	2.57 (1.55-4.27)	< 0.001^a
Peritoneal effusion	0.98 (0.55-1.75)	0.941	1.44 (0.67-3.11)	0.349	1.20 (0.70-2.05)	0.505	3.02 (1.70-5.36)	< 0.001^a
Localized complications	2.07 (1.07-4.00)	0.031^a	3.04 (1.53-6.06)	0.002^a	0.82 (0.47-1.42)	0.476	2.06 (1.18-3.59)	0.011^a
APFC	2.73 (1.50-4.96)	0.001^a	2.61 (0.98-6.99)	0.055	0.96 (0.54-1.71)	0.889	0.82 (0.46-1.46)	0.499
ANC	1.02 (0.59-1.79)	0.963	1.47 (0.71-3.05)	0.298	0.75 (0.45-1.25)	0.271	2.32 (1.37-3.94)	0.002^a
PPC	0.48 (0.13-1.74)	0.484	0.89 (0.24-3.24)	0.855	1.45 (0.54-3.89)	0.461	0.58 (0.21-1.58)	0.288
Systemic complications	1.81 (1.05-3.14)	0.034^a	2.86 (1.40-5.82)	0.004^a	1.81 (1.09-2.98)	0.021^a	2.38 (1.43-3.93)	0.001^a
Respiratory failure	2.16 (1.15-4.04)	0.016^a	2.08 (0.77-5.60)	0.146	1.40 (0.76-2.57)	0.276	4.94 (2.35-10.37)	< 0.001^a
Renal failure	2.06 (1.02-4.14)	0.044^a	2.56 (0.75-8.75)	0.133	0.85 (0.43-1.71)	0.654	3.40 (1.54-7.49)	0.002^a
Circulatory failure	1.08 (0.36-3.21)	0.896	3.02 (0.39-23.48)	0.292	0.55 (0.19-1.64)	0.283	2.74 (0.86-8.73)	0.089
SIRS	1.39 (0.81-2.37)	0.235	3.04 (1.53-6.06)	0.002^a	1.84 (1.12-3.03)	0.017	1.76 (1.07-2.90)	0.026^a
Sepsis	0.71 (0.22-2.25)	0.560	1.47 (0.32-6.69)	0.618	1.13 (0.42-3.02)	0.814	2.99 (0.95-9.43)	0.062
ACS	1.11 (0.43-2.84)	0.829	1.23 (0.35-4.38)	0.745	1.57 (0.65-3.78)	0.315	2.47 (0.93-6.53)	0.069
ARDS	1.92 (0.69-5.35)	0.214	1.37 (0.30-6.25)	0.688	1.28 (0.46-3.51)	0.637	4.02 (1.12-14.47)	0.033^a
MODS	1.74 (0.81-3.73)	0.156	3.18 (0.73-13.86)	0.124	0.84 (0.40-1.79)	0.654	3.54 (1.47-8.52)	0.005^a
SAP	1.85 (1.00-3.43)	0.050	1.83 (0.73-4.59)	0.201	1.17 (0.65-2.12)	0.598	4.32 (2.16-8.66)	< 0.001^a
ICU admission	1.69 (0.90-3.17)	0.102	2.14 (0.80-5.74)	0.132	1.47 (0.80-2.69)	0.211	3.91 (1.94-7.85)	< 0.001^a

P < 0.05.

Adjusted for age and sex. OR: Odds ratio; HDL-C: High-density lipoprotein cholesterol; APFC: Acute peripancreatic fluid collection; ANC: Acute necrotic collection; PPC: Pancreatic pseudocyst; SIRS: Systemic inflammatory response syndrome; ACS: Abdominal compartment syndrome; ARDS: Acute respiratory distress syndrome; MODS: Multiple organ dysfunction syndrome; SAP: Severe acute pancreatitis; ICU: Intensive care unit.