Fig. 2.

Effects of avermectin B1 on the migration and invasion of osteosarcoma. (A) Transwell assays were conducted to determine the migrative and invasive ability of MNNG, MG63 and U2OS cell lines. (B) Wound healing assay of osteosarcoma cell lines treated with avermectin B1. (C) Quantification of migrated and invaded cells. (D) Quantification of the wound healing rate. Data are shown as the means ± SDs with scatter plots from at least three independent experiments. Statistical analysis was performed using one-way ANOVA followed by post-hoc tests. *p < 0.05, **p < 0.01, *** p < 0.001