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. 2024 Sep 15;16(9):3781–3797. doi: 10.4251/wjgo.v16.i9.3781

Table 1.

Summary of various erythropoietin-induced hepatocyte receptor and their implicated roles depending on cancer type

Cancer type
Eph receptor
Aberrant function
Role of Eph receptor
Colorectal cancer EphA1 Overexpressed in early stages; low expression in later stages Tumour suppressive
EphA2 Overexpressed in early stages; low expression in later stages Tumour suppressive
EphA3 Low expression Tumour suppressive
EphA4 Overexpressed Tumour promoting
EphA7 Low expression Tumour suppressive
EphB2 Overexpressed in early stages; low expression in later stages Tumour suppressive
EphB3 Overexpressed in early stages; low expression in later stages Tumour suppressive
EphB4 Overexpressed Tumour promoting
EphB6 Low expression Tumour suppressive

Eph: Erythropoietin-induced hepatocyte.