Table 2.

Univariate and multivariate analysis of serum alkaline phosphatase and γ-glutamyltransferase levels and overall survival before treatment

Project	Single factor analysis (95%CI)	P value	Multivariate analysis (95%CI)	P value
ALP (> 135 U/L vs ≤ 135 U/L	1.988 (1.313-3.008)	0.001	1.766 (1.068-2.921)	0.027
GGT (> 45 U/L vs ≤ 45 U/L)	2.816 (1.741-4.556)	0.001	2.312 (1.367-3.912)	0.002
Cholinesterase (< 4300 U/L vs ≥ 4300 U/L)	1.948 (1.328-2.857)	0.001	1.312 (0.815-2.113)	0.264
ALT (> 40 U/L vs ≤ 40 U/L)	1.716 (1.125-2.617)	0.012	1.531 (0.933-2.511)	0.092
AST (> 35 U/L vs ≤ 35 U/L)	1.479 (0.937-2.334)	0.093	0.819 (0.483-1.390)	0.460
TBil (> 30 μmol/L vs ≤ 30 μmol/L)	2.098 (1.338-3.288)	0.001	1.202 (0.689-2.096)	0.518
Alb (< 40 g/L vs ≥ 40 g/L)	1.274 (0.830-1.956)	0.269	0.814 (0.502-1.319)	0.403

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; GGT: γ-glutamyltransferase; 95%CI: 95% confidence interval.