Table 3.
Association between sleep and nighttime behavior and dyslipidemia at baseline and 12 months follow-up
| Characteristic | Model 1 | Model 2 | Model 3 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | Event | ORa (95% CIa) | P-value | N | Event | ORa (95% CIa) | P-value | N | Event | ORa (95% CIa) | P-value | |
| Sleep disorders at baseline | ||||||||||||
| Cholesterol | 2,216 | 357 | 0.744 | 2,031 | 335 | 0.412 | 2,031 | 335 | 0.571 | |||
| Normal (< 200 mg/dL) | — | — | — | |||||||||
| High (≥ 200 mg/dL) | 1.04 (0.83, 1.31) | 0.90 (0.70, 1.16) | 0.93 (0.72, 1.20) | |||||||||
| Triglyceride | 2,216 | 357 | 0.003 | 2,031 | 335 | 0.016 | 2,031 | 335 | 0.048 | |||
| Normal (< 150 mg/dL) | — | — | — | |||||||||
| High (≥ 150 mg/dL) | 1.43 (1.13, 1.80) | 1.36 (1.06, 1.74) | 1.29 (1.00, 1.66) | |||||||||
| BMI (continuous value) | 2,216 | 357 | 1.03 (1.00, 1.05) | 0.030 | 2,031 | 335 | 1.03 (1.01, 1.06) | 0.008 | — | |||
| BMI categories | 2,216 | 357 | 0.095 | 2,031 | 335 | 0.029 | — | |||||
| Healthy Weight | — | — | — | |||||||||
| Underweight | 1.12 (0.26, 3.43) | 0.857 | 0.95 (0.21, 2.99) | 0.934 | — | |||||||
| Overweight | 1.12 (0.86, 1.47) | 0.391 | 1.14 (0.86, 1.51) | 0.371 | — | |||||||
| Obesity | 1.47 (1.09, 1.99) | 0.012 | 1.65 (1.18, 2.29) | 0.003 | — | |||||||
| Incident sleep disorders at 12 months follow-up | ||||||||||||
| Cholesterol | 1,550 | 187 | 0.719 | 1,468 | 178 | 0.641 | 1,468 | 178 | 0.706 | |||
| Normal (< 200 mg/dL) | — | — | — | |||||||||
| High (≥ 200 mg/dL) | 1.06 (0.77, 1.44) | 1.08 (0.77, 1.52) | 1.07 (0.76, 1.50) | |||||||||
| Triglyceride | 1,550 | 187 | 0.066 | 1,468 | 178 | 0.167 | 1,468 | 178 | 0.122 | |||
| Normal (< 150 mg/dL) | — | — | — | |||||||||
| High (≥ 150 mg/dL) | 1.35 (0.98, 1.85) | 1.27 (0.90, 1.76) | 1.31 (0.93, 1.83) | |||||||||
| BMI (continuous value) | 1,550 | 187 | 0.98 (0.95, 1.01) | 0.202 | 1,468 | 178 | 0.98 (0.95, 1.02) | 0.417 | — | |||
| BMI categories | 1,550 | 187 | 0.046 | 1,468 | 178 | 0.090 | — | |||||
| Healthy Weight | — | — | — | |||||||||
| Underweight | 4.81 (1.23, 16.4) | 0.014 | 4.15 (1.04, 14.6) | 0.030 | — | |||||||
| Overweight | 1.34 (0.95, 1.90) | 0.101 | 1.35 (0.93, 1.95) | 0.114 | — | |||||||
| Obesity | 0.97 (0.61, 1.51) | 0.891 | 1.02 (0.62, 1.66) | 0.941 | — | |||||||
Model 1: crude logistic regression analysis
Model 2: adjusted for age, sex, racial profile, educational level, cognition-related main diagnosis, geriatric depression scale total score, APOE ε4 status
Model 3: model 2 + BMI
aOR Odds Ratio, CI Confidence Interval, BMI Body Mass Index